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Yu-Jen Chen Selected Research

N-farnesyl-norcantharimide

5/2020Inhibition of Jurkat T Cell Growth by N-farnesyl-norcantharimide Through Up-regulation of Tumor Suppressor Genes and Down-regulation of Genes for Steroid Biosynthesis, Metabolic Pathways and Fatty Acid Metabolism.
6/2015N-Farnesyloxy-norcantharimide and N-farnesyl-norcantharimide inhibit the progression of leukemia and increase survival days in a syngeneic mouse leukemia model.

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Yu-Jen Chen Research Topics

Disease

103Neoplasms (Cancer)
10/2022 - 04/2002
17Uterine Cervical Neoplasms (Cancer of the Cervix)
02/2022 - 06/2006
15Body Weight (Weight, Body)
08/2022 - 07/2004
14Hepatocellular Carcinoma (Hepatoma)
03/2021 - 03/2005
13Leukemia
11/2019 - 03/2005
12Neoplasm Metastasis (Metastasis)
01/2022 - 12/2003
12Squamous Cell Carcinoma of Head and Neck
06/2021 - 12/2011
11Adenocarcinoma
01/2020 - 01/2004
10Esophageal Neoplasms (Esophageal Cancer)
02/2020 - 09/2005
8Colorectal Neoplasms (Colorectal Cancer)
04/2020 - 01/2008
8Carcinoma (Carcinomatosis)
12/2016 - 06/2006
7Pain (Aches)
01/2019 - 11/2003
7Lung Neoplasms (Lung Cancer)
01/2018 - 06/2004
6Breast Neoplasms (Breast Cancer)
01/2022 - 11/2003
6Obesity
07/2021 - 01/2008
6Inflammation (Inflammations)
05/2021 - 01/2014
6Ataxia Telangiectasia (Louis Bar Syndrome)
01/2020 - 09/2007
6BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
11/2019 - 01/2011
6Pancreatic Neoplasms (Pancreatic Cancer)
01/2014 - 01/2008
5Diarrhea
01/2022 - 02/2008
5Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2020 - 12/2005
5Mouth Neoplasms (Oral Cancer)
02/2019 - 01/2017
4Fatigue
08/2022 - 02/2012
4Infections
07/2021 - 03/2008
4Metabolic Syndrome (Dysmetabolic Syndrome X)
07/2021 - 12/2012
4Heart Failure
06/2021 - 05/2017
4Glioblastoma (Glioblastoma Multiforme)
03/2015 - 09/2012
4Glioma (Gliomas)
03/2015 - 07/2008
3Hypopharyngeal Neoplasms
10/2022 - 06/2005
3Prostatic Neoplasms (Prostate Cancer)
01/2022 - 01/2018
3Fibrosis (Cirrhosis)
01/2022 - 12/2009
3Mucositis
05/2021 - 08/2005
3Esophageal Squamous Cell Carcinoma
01/2021 - 01/2019
3Thrombosis (Thrombus)
12/2020 - 01/2009
3Stroke (Strokes)
10/2020 - 01/2018
3Squamous Cell Carcinoma (Epidermoid Carcinoma)
02/2020 - 10/2013
3Melanoma (Melanoma, Malignant)
01/2020 - 01/2013
3Rectal Neoplasms (Rectal Cancer)
12/2016 - 09/2006
3Head and Neck Neoplasms (Head and Neck Cancer)
01/2015 - 10/2008
3Necrosis
01/2014 - 08/2009
3Polyploidy
10/2013 - 09/2009
3Blister (Bulla)
01/2013 - 03/2005
2Type 2 Diabetes Mellitus (MODY)
06/2021 - 04/2018

Drug/Important Bio-Agent (IBA)

11Fluorouracil (Carac)FDA LinkGeneric
01/2022 - 01/2004
10Proteins (Proteins, Gene)FDA Link
01/2020 - 09/2007
9Biomarkers (Surrogate Marker)IBA
10/2022 - 02/2016
8Pharmaceutical PreparationsIBA
10/2018 - 03/2005
8norcantharidinIBA
06/2015 - 03/2005
7DNA (Deoxyribonucleic Acid)IBA
01/2020 - 05/2009
7Cisplatin (Platino)FDA LinkGeneric
03/2017 - 09/2005
6Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2022 - 06/2006
6CytokinesIBA
05/2021 - 06/2006
6caffeic acid phenethyl esterIBA
01/2017 - 12/2003
5InflammasomesIBA
01/2021 - 10/2016
5Transforming Growth Factors (Transforming Growth Factor)IBA
11/2020 - 08/2005
5Radiation-Sensitizing AgentsIBA
02/2019 - 11/2003
5CreatinineIBA
02/2018 - 08/2005
5Telomerase (Telomerase Reverse Transcriptase)IBA
03/2014 - 07/2006
4tetrandrineIBA
01/2022 - 12/2002
4Sorafenib (BAY 43-9006)FDA Link
12/2020 - 01/2009
4Biological ProductsIBA
01/2020 - 01/2013
4Messenger RNA (mRNA)IBA
02/2019 - 07/2008
4armillaridinIBA
01/2019 - 01/2013
4Alanine Transaminase (SGPT)IBA
02/2018 - 08/2005
4Phosphotransferases (Kinase)IBA
01/2016 - 05/2009
4WW Domain-Containing OxidoreductaseIBA
03/2015 - 09/2012
4Tyrosine Kinase InhibitorsIBA
07/2014 - 09/2009
4Cantharidin (Cantharides)IBA
01/2013 - 03/2005
3AlbuminsIBA
01/2022 - 12/2009
3Hepatitis B Surface Antigens (HBsAg)FDA Link
01/2022 - 11/2008
3Oxygen (Dioxygen)IBA
06/2021 - 01/2018
3CaspasesIBA
02/2020 - 01/2008
3Leucovorin (Folinic Acid)FDA Link
01/2020 - 09/2006
3Oxaliplatin (Eloxatin)FDA LinkGeneric
01/2020 - 05/2009
3Annexin A5IBA
01/2020 - 04/2012
36-(Methylsulfinyl)hexyl isothiocyanateIBA
11/2019 - 01/2014
3Checkpoint Kinase 2IBA
02/2019 - 05/2009
3Conditioned Culture MediaIBA
02/2018 - 11/2008
3CateninsIBA
01/2018 - 01/2013
3Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA
02/2017 - 12/2012
3Propolis (Bee Bread)IBA
01/2017 - 01/2008
3Indicators and Reagents (Reagents)IBA
06/2016 - 11/2012
3Doxorubicin (Adriamycin)FDA LinkGeneric
03/2016 - 01/2012
3Contrast MediaIBA
01/2016 - 11/2013
3Lapatinib (GW572016)FDA Link
01/2016 - 01/2011
3Epidermal Growth Factor (EGF)IBA
07/2014 - 01/2011
3Transforming Growth Factor beta1 (TGF beta 1)IBA
10/2008 - 08/2005
2Hormones (Hormone)IBA
02/2022 - 01/2022
2BilirubinIBA
01/2022 - 10/2021

Therapy/Procedure

47Radiotherapy
01/2022 - 04/2002
31Therapeutics
01/2022 - 12/2002
17Intensity-Modulated Radiotherapy (Radiotherapy, Intensity Modulated)
02/2022 - 01/2009
16Chemoradiotherapy
10/2022 - 09/2005
12Drug Therapy (Chemotherapy)
05/2021 - 06/2005
5Aftercare (After-Treatment)
11/2020 - 11/2003
4Neoadjuvant Therapy
02/2020 - 10/2016
4Chinese Traditional Medicine (Traditional Chinese Medicine)
10/2017 - 10/2009
4Brachytherapy
02/2016 - 10/2007
3Chemoprevention
01/2013 - 12/2005
2Hysterectomy
07/2021 - 11/2010